Longevity · Research kit
MOTS-c
Mitochondrial-derived peptide used in exercise-mimetic and AMPK research.
- Class
- Mitochondrial-derived peptide (16 aa)
- Half-life
- Short
- Kit
- 10 vials
- Use
- Research only
Kit of 10 vials · 40mg per vial
Best value€419.00
€41.90 per vial · €1.05/mg
Sold as 10-vial kits · minimum order
We don't sell single vials. Every order is a sealed 10-vial research kit, with the selected vial size and complete kit price shown above.
- ✓ Clear unit pricing — the kit, per-vial and per-mg prices are shown together for comparison.
- ✓ Batch records — review published independent test results in the COA library when available.
- ✓ Storage guidance — handling and storage information is available in the research guide library.
- ✓ Tracked dispatch — choose the available shipping route during checkout.
Choose your kit size
1 kit = 10 vials. Bigger vials = lower price per vial.
- ✓ Sealed 10-vial kit (small glass bottles, lyophilised powder)
- ✓ Published Certificate of Analysis (COA) where available for this product
- ✓ Dispatches from Germany, the USA or China in 1–3 working days · 5–18 day tracked delivery
- ✓ Tracked dispatch with support available if a delivery issue occurs
- ! You'll also need bacteriostatic water to mix your peptides
- Batch testingPublished COAs
- 5–18 day deliveryTracked, discreet
- Human supportDelivery help
Card or bank-transfer checkout · Wise shown first · Germany, USA or China dispatch within 1–3 working days · 5–18 business days from active tracking
Estimated delivery
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€ Cost per mg, kit by kit
Every MOTS-c kit ships as 10 vials. The sums below show what each strength works out to, so you can compare cost per milligram for yourself; bigger vials normally cost less per mg.
Kit price
€419.00
40 mg × 10 vials
Per vial
€41.90
€419.00 ÷ 10 vials
Total mg in kit
400 mg
40 mg × 10
Per mg
€1.05
€419.00 ÷ 400 mg
Compare every kit
| Kit | Kit price | Per vial | Per mg |
|---|---|---|---|
| 10 mg / vial | €279.00 | €27.90 | €2.79 |
| 40 mg / vialBest €/mg | €419.00 | €41.90 | €1.05 |
What is MOTS-c?
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region. Research describes AMPK activation and modulation of the folate/methionine cycle in exercise-mimetic models.
Mechanism of action
Activates AMPK and modulates folate/methionine cycle.
Primary research areas
Metabolic flexibility, exercise mimetic studies.
Research notes
- Encoded within mitochondrial DNA, distinguishing it from nuclear-encoded peptides.
MOTS-c: expanded research context
MOTS-c is a 16-amino-acid mitochondrial-derived peptide encoded within the 12S rRNA region of mitochondrial DNA. It is one of a small family of mitochondrial peptides (with humanin and SHLPs) that appear to signal in an endocrine-like manner about mitochondrial metabolic state. Research interest centres on AMPK activation, glucose homeostasis and exercise-mimetic pathways.
In preclinical work, MOTS-c improved insulin sensitivity, protected against age-related insulin resistance and enhanced physical capacity in aged mice. Circulating levels decline with age in humans. Published proteomic work links MOTS-c to skeletal-muscle metabolic adaptation and exercise-response gene programmes.
Literature for orientation
A short reading list of papers that mention MOTS-c. These are listed so you can find the primary sources yourself — they are not claims about our stock. Look up the full text on PubMed or via the journal DOI.
MOTS-c improves insulin sensitivity (mouse)
Cell Metabolism · 2015 (Lee et al.)
Original characterisation of MOTS-c — systemic administration prevented diet-induced obesity and improved insulin sensitivity via AMPK activation in a rodent model.
MOTS-c enhances physical capacity in aged mice
Nature Communications · 2021
Late-life MOTS-c administration improved treadmill capacity, grip strength and metabolic markers in aged mice.
Circulating MOTS-c and age in humans
Journal of Gerontology · 2019
Cross-sectional human data showing progressive decline of circulating MOTS-c with chronological age.
MOTS-c and skeletal-muscle exercise adaptation
American Journal of Physiology · 2020
MOTS-c expression rose in response to acute exercise and modulated muscle transcriptional programmes for metabolic adaptation.
What to expect from Bio Mech
Documentation, stated plainly
We only show a laboratory report when it has been matched to Bio Mech stock. Ask about the batch you are ordering before you pay.
Sealed kits of ten vials
Freeze-dried material in stoppered vials, each carrying a batch code. Move it to cold storage when the parcel arrives.
Tracked, plain parcels
Sent from whichever dispatch point holds stock for your country, in unmarked packaging, with a tracking number.
Several ways to pay
Wise, Revolut, Monzo, bunq or a direct bank transfer. We never see or keep your card details.
Ordering, step by step
- 1
Pick your MOTS-c kit above
Each kit contains 10 vials. Choose your strength — bigger vials give you a lower €/mg.
- 2
Enter your delivery details
Checkout gives you an order reference straight away, so your payment can be matched to you.
- 3
Choose a payment option
Pick Wise, Revolut, Monzo, bunq or bank transfer. Any trouble paying, contact support and we will help.
- 4
Follow your parcel
Once it ships we send your tracking number. Delivery takes 5–18 business days from the moment tracking becomes active.
Common questions
Research use only
Bio Mech sells MOTS-c only for laboratory research by qualified people. This page is background reading, not advice of any kind, and it does not recommend use in people or animals. Any figures quoted from papers are rough values taken from the literature.
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More on MOTS-c and related research
MOTS-c — shipped to research hubs worldwide
Delivery notes for MOTS-c by destination: pick a place to see its delivery window, payment options and customs pointers.
- MOTS-c for Costa Rica researchers
- MOTS-c for Delaware researchers
- MOTS-c for Dundee researchers
- MOTS-c for Estonia researchers
- MOTS-c for Florida researchers
- MOTS-c for Germany researchers
- MOTS-c for Glasgow researchers
- MOTS-c for Hong Kong researchers
- MOTS-c for Iceland researchers
- MOTS-c for Indonesia researchers
- MOTS-c for Jaén researchers
- MOTS-c for Kentucky researchers
- MOTS-c for Latvia researchers
- MOTS-c for Lisbon researchers
- MOTS-c for London researchers
- MOTS-c for Maine researchers
- MOTS-c for Maryland researchers
- MOTS-c for Michigan researchers
- MOTS-c for Minnesota researchers
- MOTS-c for Mongolia researchers
- MOTS-c for Murcia researchers
- MOTS-c for New Hampshire researchers
- MOTS-c for Newcastle researchers
- MOTS-c for Norway researchers
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Cite this reference
Researching MOTS-c?
Need to reference this page? Copy a citation or a plain HTML link below.
Bio Mech Peptides. (2026-10-06). MOTS-c — HPLC-verified research peptide. https://biomechpeptides.com/peptides/mots-c
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Order in 3 steps · tracked delivery
Order MOTS-c for laboratory research
Batch documentation is provided on request — no laboratory reports have yet been verified for publication against Bio Mech stock. Dispatch is tracked on every order; allow 5–18 business days once tracking is active. Supplied for in-vitro research use only.
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Tracked dispatch
Tracking on every order; 5–18 business days once tracking is active.
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Reconstitution supplies (optional)
Sold separately and never added automatically. Solvent choice depends on the compound — check its COA or handling sheet before choosing.